Unbound drug fractions in naive and EAE mouse brain homogenate
Data are the average from five replicate incubations ± S.D.
| Name | % Unbound Fraction in Brain Homogenate | |
|---|---|---|
| Naive | EAE | |
| Naproxen | 49.7 ± 6.6 | 53.7 ± 9.4 |
| Loperamide | 0.65 ± 0.02 | 0.70 ± 0.07 |
| GSK-A | 0.0053 ± 0.0012 | 0.0049 ± 0.0014 |
| GSK-B | 0.22 ± 0.03 | 0.17 ± 0.01 |