TABLE 1

Pharmacokinetic parameters estimated from single oral administration of GDC-0941 to nu/nu mice

Parameter	Estimate	CV
		%
k_a (h⁻¹)	10.4	35.4
k_e (h⁻¹)	0.23	4.07
V/F (l/kg)	19.9	9.77

CV, coefficient of variation.