Comparison between the actual and classified pathways: drugs not classified as any pathway and the reasons for such classification
| Charge and Drug Name | Actual Pathway | Log D | fup | MW |
|---|---|---|---|---|
| Cation/neutral | ||||
| Eplerenone | 3A4 | ↓ | ↑ | |
| Oxycodone | 3A4 | ↓ | ↑ | |
| Tamsulosin | 3A4 | ↓ | ||
| Chlorpheniramine | 2D6 | ↑ | ||
| Galantamine | 2D6 | ↑ | ||
| Propranolol | 2D6 | ↑ | ||
| Venlafaxine | 2D6 | ↑ | ||
| Digoxin | Renal | ↑ | ↑ | |
| Topiramate | Renal | ↑ | ||
| Anion | ||||
| Montelukast | 2C9 | ↑ | ↓ | ↑ |
↑, the parameter of the drug is above the boundary of its actual pathway; ↓, the parameter of the drug is below the boundary of its actual pathway.