TABLE 1

Kinetic parameters for phenacetin and APAP hydrolase activities in HLM

KmVmaxCLint
mMnmol/(min · mg)μl/(min · mg)
Phenacetin3.30 ± 0.163.58 ± 0.201.08 ± 0.02*
APAPN.A.N.A.0.02 ± 0.00

  • N.A., not applicable.

  • ↵* P < 0.001 compared with APAP.