TABLE 2

The uptake of [14C] cerivastatin in sandwich-cultured human hepatocytes

DonorPercentage of Total Uptake of Cerivastatin
Passive DiffusionTransporter-Mediated
Hu0837 (freshly isolated)73.3 ± 2.826.7 ± 2.8
NLX (cryopreserved)77.4 ± 11.122.6 ± 11.1