Transport of quercetin across MDCK cell monolayers transfected with empty vector or Bcrp1
The apparent permeability was calculated as described under Materials and Methods.
| Quercetin (10 μM) | Papp, A-B | Papp, B-A | Transport Ratio (Papp, B-A/Papp, A-B) | |
|---|---|---|---|---|
| cm/s × 10−6 | ||||
| Without K | MDCK/Mock | 11.8 ± 0.35 | 10.0 ± 0.72 | 0.85 |
| Without K | MDCK/Bcrp1 | 0.232 ± 0.078 | 21.9 ± 4.4 | 97.5 |
| With K | MDCK/Bcrp1 | 2.83 ± 0.65 | 23.7 ± 11 | 8.37 |
K, kaempferol.