TABLE 3

fup values under different buffer/atmospheric conditions yielding different Postdialysis Plasma pH values

Marker in Fig. 4	Compound	pK_a	Class	fup ± S.D.
Marker in Fig. 4	Compound	pK_a	Class	Buffer 2, Normal Atmospheric Conditions; Postdialysis Plasma pH 7.22	Buffer 3, 5% CO₂; Postdialysis Plasma pH 7.40	Buffer 4, 5% CO₂; Postdialysis Plasma pH 7.63	Buffer 1, Normal Atmospheric Conditions; Postdialysis Plasma pH 7.72
A	Diazepam	3.4	Neutral	0.019 ± 0.002	0.016 ± 0.003	0.019 ± 0.003	0.023 ± 0.001
B	Diclofenac	4.0	Acid	0.003 ± 0.001	0.007 ± 0.000	0.005 ± 0.002	0.004 ± 0.002
C	Cinoxacin	4.7	Acid	0.251 ± 0.104	0.214 ± 0.016	0.230 ± 0.039	0.266 ± 0.025
D	Warfarin	4.9	Acid	0.009 ± 0.002	0.014 ± 0.003	0.013 ± 0.003	0.006 ± 0.002
E	Nicardipine	7.2	Base	0.008 ± 0.002	0.005 ± 0.001	0.008 ± 0.002	0.003 ± 0.001
F	Mirtazapine	7.3	Base	0.320 ± 0.025	0.286 ± 0.034	0.266 ± 0.058	0.160 ± 0.045
G	Buspirone	7.3	Base	0.333 ± 0.022	0.277 ± 0.022	0.261 ± 0.039	0.214 ± 0.041
H	Clozapine	7.5	Base	0.101 ± 0.012	0.081 ± 0.011	0.058 ± 0.011	0.042 ± 0.009
I	Diltiazem	8.0	Base	0.417 ± 0.038	0.349 ± 0.015	0.350 ± 0.030	0.298 ± 0.038
J	Quinidine	8.1	Base	0.274 ± 0.020	0.218 ± 0.001	0.299 ± 0.060	0.251 ± 0.026
K	Tranylcypromine	8.2	Base	0.630 ± 0.027	0.612 ± 0.107	0.530 ± 0.051	0.490 ± 0.096
L	Haloperidol	8.3	Base	0.223 ± 0.032	0.161 ± 0.018	0.164 ± 0.027	0.124 ± 0.014
M	Risperidone	8.3	Base	0.276 ± 0.029	0.186 ± 0.030	0.222 ± 0.051	0.163 ± 0.044
N	Trimipramine	8.4	Base	0.106 ± 0.016	0.054 ± 0.013	0.052 ± 0.004	0.037 ± 0.016
O	Verapamil	8.7	Base	0.233 ± 0.035	0.160 ± 0.016	0.154 ± 0.022	0.137 ± 0.021
P	Midazolam	9.0	Base	0.034 ± 0.005	0.036 ± 0.004	0.041 ± 0.009	0.019 ± 0.006
Q	Imipramine	9.4	Base	0.220 ± 0.016	0.181 ± 0.030	0.172 ± 0.043	0.105 ± 0.034
R	Paroxetine	9.5	Base	0.136 ± 0.011	0.099 ± 0.026	0.089 ± 0.020	0.074 ± 0.006
S	Propranolol	9.6	Base	0.315 ± 0.021	0.231 ± 0.046	0.213 ± 0.015	0.216 ± 0.031
T	Milnacipran	9.7	Base	0.809 ± 0.048	0.837 ± 0.071	0.777 ± 0.110	0.828 ± 0.024
U	Fluoxetine	10.1	Base	0.079 ± 0.015	0.056 ± 0.006	0.063 ± 0.011	0.040 ± 0.013
	Carbamazepine		Neutral	0.303 ± 0.021	0.291 ± 0.029	0.288 ± 0.053	0.299 ± 0.023