Incubation Time | Km | Vmax | CLint | CLint Ratio (Liver/Intestine) | |
---|---|---|---|---|---|
min | μM | pmol per min/mg | μl per min/mg | ||
Dog | |||||
Intestinal microsomes | 15 | 42.7 ± 1.0 | 49.8 ± 2.0 | 1.2 ± 0.0 | 17.2 |
Liver microsomes | 15 | 18.5 ± 0.6 | 379.9 ± 20.7 | 20.6 ± 0.5 | |
Human | |||||
Intestinal microsomes | 15 | 80.4 ± 11.5 | 89.2 ± 1.3 | 1.1 ± 0.1 | 8.7 |
Liver microsomes | 15 | 26 | 247 | 9.6 |
Data from Rehmel et al. (2006).