P450 | 16α-Hydroxytestosterone | 16β-Hydroxytestosterone | ||||
---|---|---|---|---|---|---|
Km | Vmax | Vmax/Km | Km | Vmax | Vmax/Km | |
WT | 13.3 ± 3 | 100 ± 2 | 7.52 | 27.7 ± 3 | 100 ± 4 | 3.61 |
2B6.4 | 99 ± 17 | 31 ± 4 | 0.31 | 29.8 ± 9 | 8.1 ± 3 | 0.27 |
2B6.6 | 20.7 ± 6 | 40 ± 7 | 3.74 | 18.1 ± 2 | 97 ± 19 | 5.36 |
2B6.9 | 10 ± 2 | 24 ± 4 | 2.4 | 40 ± 5 | 46 ± 7 | 1.15 |
WT, wild-type.