TABLE 1

Summary of the study design including information on the average dose administered and the average weight of the animals

Data are presented as the mean ± S.D.

No. of AnimalsInvestigational DrugsDoseDoseWeightSite of Administration
mgμmolkg
T15Finasteride20 ± 154 ± 227 ± 4Jejunum
T25Finasteride21 ± 156 ± 326 ± 1Jejunum
Ketoconazole250 ± 30470 ± 5626 ± 1Jejunum
Intravenous3Finasteride5 ± 0.214 ± 0.525 ± 1Intravenousa
  • a Bolus dose given through a central vein catheter.