Brivanib | 371 | 353, 313, 164 | | Rat, monkey, human |
M2 | 489 | 313, 285, 175, 164 | O-Dealkylation, glucuronidation | Rat, monkey, human |
M6 | 393 | 313, 285, 175, 164 | O-Dealkylation, sulfation | Rat, monkey, human |
M7 | 387 | 369, 329, 311 | Hydroxylation | Rat, monkey |
M9 | 313 | 285, 164, 149 | O-Dealkylation | Rat, monkey |
M13 | 329 | 182, 149 | O-Dealkylation, hydroxylation | Rat |
M17 | 409 | 329, 311 | O-Dealkylation, hydroxylation, sulfation | Monkey |
M19 | 467 | 387, 369, 329 | Hydroxylation, sulfation | Rat, monkey, human |
M25 | 451 | 371, 353, 313 | Sulfation | Rat, monkey, human |
M26 | 401 | 383, 343 | Carboxylation | Rat, monkey, human |
M28 | 547 | 371, 353, 313 | Glucuronidation | Monkey, human |
M30 | 371 | 313, 148 | Carboxylation, decarboxylation | Rat, monkey |
M31 | 369 | 312, 148 | Oxidation to a ketone | Rat, monkey, human |
M32 | 423 | 343, 325 | O-Dealkylation, sulfation, carboxylation | Rat, monkey, human |
M33 | 481 | 401, 383, 343 | Carboxylation, sulfation | Monkey, human |
M34 | 343 | 325 | O-Dealkylation, carboxylation | Rat |