TABLE 1

Body, liver, and kidney weight and blood glucose levels for DIO and lean mice

Male C57BL/6J mice were fed a 60% kcal diet (DIO) or a 10% kcal diet from 6 to 21 weeks of age. Livers, kidneys, and blood were collected at 21 weeks of age. All weights are expressed as the mean ± S.E.M.

StrainLiver WeightKidney WeightAverage Body WeightLiver/Body WeightMean Blood Glucose Levels
g%mg/dl
Lean1.22 ± 0.0310.32 ± 0.01529.68 ± 0.154.12 ± 0.099145.4 ± 6.06
DIO1.65 ± 0.0580.40 ± 0.01741.50 ± 0.70*3.98 ± 0.093198.6 ± 9.65*
  • * Statistically significant difference of parameters between control and DIO mice (p ≤ 0.05).