Demographic and metabolism data for plasma samples in this study
| Sample | Gender | Age | Protein Concentration | CPF-oxon Hydrolysis Vmax | CPF-oxon Hydrolysis Km | CPF-Oxon Hydrolysis Cli |
|---|---|---|---|---|---|---|
| years | mg/ml | nmol · min−1 · ml−1 | μM | μl · min−1 · mg microsomal protein−1 | ||
| BRH338829 | F | 0.01 | 49.44 | 802 | 118.46 | 6771 |
| BRH338830 | F | 0.02 | 48.13 | 2410 | 283.13 | 8513 |
| BRH338828 | F | 0.06 | 53.91 | 1938 | 114.32 | 16950 |
| BRH338832 | F | 0.17 | 56.74 | 1919 | 132.53 | 14482 |
| BRH338831 | M | 0.42 | 49.73 | 2438 | 146.15 | 16679 |
| BRH338837 | M | 0.58 | 66.87 | 4873 | 175.21 | 27814 |
| BRH338833 | F | 0.67 | 46.20 | 1241 | 527.12 | 2354 |
| BRH338836 | M | 0.67 | 69.01 | 4900 | 205.94 | 23793 |
| BRH338834 | M | 0.83 | 69.30 | 4027 | 136.12 | 29585 |
| BRH338835 | M | 0.83 | 75.05 | 2460 | 192.25 | 12795 |
| BRH338841 | M | 2 | 77.95 | 3082 | 169.61 | 18169 |
| BRH338839 | M | 4 | 80.77 | 598 | 230.75 | 2591 |
| BRH338842 | M | 9 | 72.75 | 6624 | 191.70 | 34555 |
| BRH338840 | M | 10 | 71.51 | 4914 | 217.85 | 22556 |
| BRH338838 | M | 12 | 95.95 | 9643 | 264.73 | 36428 |
| BRH338843 | F | 16 | 90.69 | 7531 | 202.66 | 37162 |
| BRH338844 | F | 17 | 84.75 | 6650 | 174.87 | 38031 |
| BRH338847 | M | 30 | 97.68 | 8849 | 203.27 | 43533 |
| BRH338846 | F | 43 | 75.47 | 6691 | 200.59 | 33358 |
| BRH338845 | F | 46 | 86.55 | 4423 | 176.51 | 25056 |
| Adult mean ± S.D. | 87 ± 8 | 6829 ± 1614 | 192 ± 15 | 35428 ± 6843 |
F, female; M, male; Cli, intrinsic clearance.