Parent or Metabolite Code | Mean Percentage of Urine Radioactivity (Mean Percentage of Administered Dose)a | ||
---|---|---|---|
Intact Male | Intact Female | BDC male | |
P | 0.04 (0.01) | 0.18 (0.05) | ND |
M1 | 1.20 (0.21) | 0.39 (0.12) | 0.28 (0.05) |
M2 | 0.72 (0.13) | 0.74 (0.23) | 0.28 (0.05) |
M4 | 12.8 (2.22) | 21.8 (6.90) | 12.8 (2.11) |
M9 | 33.0 (5.80) | ND | 32.9 (5.63) |
M11 | 0.58 (0.10) | 0.81 (0.25) | 1.12 (0.19) |
M12 | 3.31 (0.58) | 9.79 (3.07) | 1.35 (0.22) |
M14 | 13.4 (2.37) | 8.21 (2.58) | 21.1 (3.56) |
M17 | 1.87 (0.33) | 0.67 (0.20) | 2.23 (0.38) |
M21 | 0.68 (0.12) | 26.0 (8.14) | 1.35 (0.22) |
M24 | 1.32 (0.24) | ND | 1.50 (0.25) |
M25 | 1.38 (0.24) | 4.83 (1.55) | 0.58 (0.11) |
M26 | 3.36 (0.59) | 3.85 (1.22) | 1.89 (0.35) |
M31 | 1.91 (0.34) | 5.65 (1.80) | 0.88 (0.16) |
M34 | 0.51 (0.09) | 5.65 (1.76) | ND |
Total Quantifiedb | 76.1 (13.3) | 88.6 (27.9) | 78.3 (13.3) |
P, parent compound; ND, not detected.
a Mean percentage of radioactivity recovered under each peak, also expressed as percentage of the administered dose in parenthesis.
b Total quantified represents the percentage of urine sample radioactivity that was assigned structures, also expressed as percentage of the administered dose.