Characteristics of 66 participants by UGT1A6 genotype
Data are means ± S.D. or n (%). No significant differences were seen between genotypes at P < 0.05.
| UGT1A6*1/*1 | UGT1A6*1/*2 | UGT1A6*2/*2 | ||||
|---|---|---|---|---|---|---|
| Men | Women | Men | Women | Men | Women | |
| n | 14 | 14 | 11 | 14 | 8 | 5 |
| Age (yr) | 31.3 ± 5.8 | 28 ± 6.0 | 28.8 ± 6.0 | 30.6 ± 5.4 | 29.9 ± 5.5 | 27.8 ± 5.5 |
| Height (cm) | 178.8 ± 6.5 | 160.7 ± 8.6 | 180.2 ± 7.8 | 169.2 ± 4.7 | 174.4 ± 9.9 | 164.9 ± 6.1 |
| Weight (kg) | 76.3 ± 10.5 | 58.1 ± 9.1 | 74.8 ± 8.8 | 67.8 ± 10.3 | 74.2 ± 11.6 | 59.8 ± 4.7 |
| Body mass index (kg/m2) | 23.8 ± 2.5 | 22.5 ± 2.6 | 23.0 ± 2.2 | 23.7 ± 3.2 | 24.3 ± 2.3 | 22.0 ± 1.0 |
| Ethnicity | ||||||
| White | 10 (71) | 8 (57) | 8 (73) | 10 (71.5) | 6 (75) | 4 (80) |
| Asian | 4 (31) | 6 (43) | 1 (8) | 3 (21.5) | 1 (12.5) | 1 (20) |
| Othera | 0 | 0 | 2 (17) | 1 (7) | 1 (12.5) | 0 |
| Distribution of UGT1A1*28 genotypes | ||||||
| 6/6 | 12 (86) | 11 (79) | 2 (18) | 2 (14) | 1 (12.5) | 0 |
| 6/7 | 2 (14) | 0 | 9 (82) | 11 (79) | 1 (12.5) | 1 (20) |
| 7/7 | 0 | 3 (21) | 0 | 1 (7) | 6 (75) | 4 (80) |
| Distribution of UGT2B15*2 genotypes | ||||||
| *1/*1 | 4 (29) | 2 (14) | 2 (18) | 5 (36) | 3 (37) | 0 |
| *1/*2 | 5 (36) | 7 (50) | 7 (64) | 5 (36) | 5 (63) | 4 (80) |
| *2/*2 | 5 (36) | 5 (36) | 2 (18) | 4 (28) | 0 | 1 (20) |
a Other category includes one black, one mixed race, one Pacific Islander, and one unreported.