Physicochemical and metabolic characteristics of the 16 drugs studied
| Compound | LogD7.4 | Polar Surface Area (Aº2) | Metabolically Stable |
|---|---|---|---|
| Atorvastatin | 1.3 | 112 | No |
| Bosentan | 1.25 | 146 | No |
| Cerivastatin | 1.9 | 100 | No |
| Clarithromycin | 1.8 | 183 | No |
| Erythromycin | 1.11 | 194 | No |
| Fexofenadine | 0.3 | 81 | Yes |
| Nateglinide | 1.22 | 66 | No |
| Olmesartan | −1.56 | 130 | Yes |
| Pitavastatin | 1.2 | 91 | Yes |
| Pravastatin | −0.4 | 124 | Yes |
| Repaglinide | 2.3 | 79 | No |
| Ritonavir | 4.8 | 146 | No |
| Rosuvastatin | −0.33 | 141 | Yes |
| Saquinavir | 4.8 | 167 | No |
| Telmisartan | 2.5 | 73 | Yes |
| Valsartan | −1.11 | 112 | Yes |