Identifications of degarelix and metabolites of degarelix using product ion mass spectrometry data
| Analyte | Precursor Ion | Characteristic Product Ions |
|---|---|---|
| m/z | m/z | |
| Degarelix | 816.4 | 121.1, 154.1, 170.1, 171.2, 186.1 (y2″), 240.1 (b1), 356.3 (y3″), 421.2 (b2), 469.4 (y4″), 569.2 (b3), 606.3 (y8″), 656.1 (b4), 674.4 (y5″), 696.9 (y9″), 794.9 (y10″), 807.9 (b10), 958.4 (b5), 976.6 1 (y6″), 1063.6 1 (y7″), 1163.6 (b6), 1211.7 (y8″), 1276.5 (b7), 1393.0 (y9″) |
| FE 200486(1–10)-OH | 816.9 | 121.1, 154.1, 170.1, 171.2, 187.1 (y2″), 240.1 (b1), 357.3 (y3″), 421.2 (b2), 470.4 (y4″), 569.2 (b3), 606.8 (y8″), 656.1 (b4), 675.4 (y5″), 697.4 (y9″), 795.4 (y10″), 807.9 (b10), 958.4 (b5), 977.6 1 (y6″), 1064.6 1 (y7″), 1163.6 (b6), 1212.7 (y8″), 1276.5 (b7) |
| FE 200486(1–9)-OH | 781.4 | 121.1, 154.1, 170.1, 171.2, 240.1 (b1), 286.3 (y2″), 399.4 (y3″), 421.2 (b2), 569.2 (b3), 604.6 (y4″), 656.1 (b4), 662.0 (y8″), 760.1 (y9″), 773.6 (b9), 906.8 (y5″), 958.4 (b5), 993.8 (y6″), 1141.9 (y7″), 1163.6 (b6), 1323.2 (y8″), 1276.5 (b7) |
| FE 200486(1–7)-OH | 1294.5 | 121.1, 154.1, 240.1 (b1), 337.2 (y2″), 421.2 (b2), 569.2 (b3), 639.3 (y3″), 656.1 (b4), 726.3 (y4″), 874.4 (y5″), 958.4 (b5), 1055.4 (y6″), 1163.6 (b6), 1251.5 (y7″), 1276.5 (b7) |
| FE 200486(1–6)-OH | 1181.4 | 121.1, 154.1, 240.1 (b1), 421.2 (b2), 526.3 (y2″), 569.2 (b3), 613.2 (y3″), 656.1 (b4), 761.3 (y4″), 942.3 (y5″), 958.4 (b5), 1139.4 (y6″), 1163.6 (b6) |
| FE 200486(1–5)-OH | 976.4 | 121.1, 154.1, 240.1 (b1), 321.2 (y1″), 408.1 (y2″), 421.2 (b2), 556.2 (y3″), 569.2 (b3), 656.1 (b4), 737.4 (y4″), 934.3 (y5″), 958.4 (b5) |
| FE 200486(1–4)-OH | 674.3 | 121.1, 154.1, 240.1 (b1), 254.1 (y2″), 421.2 (b2), 435.1 (y3″), 569.2 (b3), 632.2 (y4″), 656.1 (b4) |