Intestinal perfusion parameters for EE, EEG, and EES
| Wild-Type Rat Jejunum | TR− Rat Jejunum | |
|---|---|---|
| EE jejunal metabolism (%) | 60 ± 10 | 45 ± 5 |
| EE jejunal permeability (10−6 cm/s) | 40.8 ± 5.6 | 40.8 ± 5.2 |
| EE influx (jejunum) (ng/min) | 6.20 ± 1.61 | 4.43 ± 0.29 |
| EE efflux (blood) (ng/min) | 2.43 ± 0.47 | 2.49 ± 0.21 |
| EEG efflux (lumen) (ng-eq/min) | 0.90 ± 0.19 | 0.48 ± 0.10* |
| EEG efflux (blood) (ng-eq/min) | 1.96 ± 0.31 | 1.32 ± 0.33 |
| EES efflux (lumen) (ng-eq/min) | N.D. | N.D. |
| EES efflux (blood) (ng-eq/min) | N.D. | N.D. |
N.D., not detected.
* p < 0.05.