TABLE 5

P values that show the difference of apparent kinetic parameters of raloxifene glucuronidation to M1 and M2 among different UGT1A1 genotypes

P*1/*1 vs. *1/*28P*1/*28 vs. *28/*28P*1/*1 vs. *28/*28
M1
    Km0.8420.7351.017
    Vmax<0.001***<0.001***<0.001***
    Clint0.003**0.015*<0.001***
M2
    Km0.5851.2841.021
    Vmax0.5630.032*0.015*
    Clint0.4720.2040.130

  • ↵* P < 0.05.

  • ↵** P < 0.01.

  • ↵*** P < 0.001.