Genotype | Time and Treatment | Putrescine | N1-AcetylSpd | Spd | Spm | N1AcTETA | TETA |
---|---|---|---|---|---|---|---|
pmol/μg protein | |||||||
Syngenic | Control | 26 ± 0 | ND | 230 ± 36 | 322 ± 26 | ND | ND |
TETA 1 h | 34 ± 3 | ND | 185 ± 4 | 247 ± 19 | 352 ± 85 | 796 ± 63 | |
TETA 2 h | ND | ND | 145 ± 42 | 287 ± 38 | 328 ± 37 | 244 ± 150 | |
TETA 4 h | ND | ND | 145 ± 52 | 306 ± 19 | 339 ± 81 | 135 ± 122 | |
SSAT1 | Control | 156 ± 50 | 82 ± 26 | 345 ± 66* | 167 ± 19** | ND | ND |
TETA 1 h | 126 ± 19 | 71 ± 6 | 311 ± 71** | 142 ± 14** | 625 ± 77* | 934 ± 74* | |
TETA 2 h | 247 ± 154 | 485 ± 363 | 364 ± 172* | 136 ± 15** | 945 ± 552 | 423 ± 170 | |
TETA 4 h | 253 ± 335 | 217 ± 93 | 233 ± 248 | 162 ± 29** | 244 ± 56 | 137 ± 133 | |
SSAT1-KO | Control | 10 ± 0 | 14 ± 4 | 284 ± 50 | 269 ± 31* | ND | ND |
TETA 1 h | ND | ND | 176 ± 9 | 238 ± 19 | 400 ± 60 | 796 ± 29 | |
TETA 2 h | ND | ND | 145 ± 28 | 302 ± 55 | 347 ± 44 | 194 ± 135 | |
TETA 4 h | ND | ND | 154 ± 53 | 302 ± 29 | 364 ± 90 | 146 ± 158 |