Gene Name | Basal Gene Expression | Fold Modulation with TRO | Fold Modulation with ROSI | Fold Modulation with MURA | Fold Modulation with TESA | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Donor 2 | Donor 4 | Donor 5 | Donor 6 | HepaRG Cells | Donor 2 | Donor 4 | Donor 5 | Donor 6 | HepaRG Cells | Donor 2 | Donor 4 | Donor 5 | Donor 6 | HepaRG Cells | Donor 2 | Donor 4 | Donor 5 | Donor 6 | HepaRG Cells | Donor 2 | Donor 4 | Donor 5 | Donor 6 | HepaRG Cells | |
PPAR target genes | |||||||||||||||||||||||||
ACADL | 609 | 602 | 342 | 386 | 33 | 1.0 | −1.7 | 1.0 | −1.2 | −1.2 | −1.3 | −1.1 | −1.2 | −1.3 | −1.6 | 1.0 | −1.2 | 1.0 | 1.1 | −1.3 | −1.1 | −1.2 | −1.1 | 1.1 | −1.3 |
ACADS | 499 | 564 | 241 | 428 | 35 | 2.7 | 2.9 | 1.1 | 1.2 | 1.3 | 1.0 | 1.1 | −1.2 | 1.1 | 1.3 | 1.2 | 1.3 | −1.1 | −1.2 | 1.6 | 1.1 | −1.2 | −1.4 | −1.6 | 1.7 |
ACOT12 | 3935 | 3086 | 1146 | 1538 | 134,526 | 1.2 | −1.6 | 1.1 | 1.2 | −1.1 | −1.1 | −1.0 | 1.1 | 1.0 | 1.2 | 1.1 | 1.3 | 1.1 | −1.2 | −1.0 | 1.2 | 1.2 | −1.1 | 1.0 | 1.8 |
ACOT2 | 13,294 | 18,468 | 13,025 | 11,174 | 10,965 | 1.2 | 1.1 | 1.1 | 1.1 | 1.0 | −1.3 | 1.1 | −1.1 | 1.2 | −1.0 | 1.4 | 1.7 | −1.0 | −1.1 | 1.2 | 1.6 | 1.5 | −1.0 | 1.2 | 1.5 |
ACSL1 | 11,507 | 18,436 | 8491 | 8619 | 2180 | −1.1 | −1.9 | 1.3 | 1.7 | 1.5 | 1.4 | 2.7 | 1.8 | 2.3 | 1.8 | 2.2 | 4.3 | 2.9 | 2.3 | 1.8 | 2.2 | 3.6 | 2.2 | 2.8 | 2.5 |
ADH4 | 1880 | 3113 | 559 | 812 | 127 | −4.2 | −4.8 | −1.0 | −2.0 | −1.8 | −3.6 | −3.3 | −1.3 | −2.5 | −3.2 | −3.6 | −3.6 | 1.1 | −1.7 | −2.0 | −4.2 | −4.1 | 1.1 | −1.7 | −3.0 |
ADFP | 3110 | 3474 | 2350 | 1281 | 19,191 | 1.6 | 1.0 | 2.6 | 2.0 | 2.9 | 3.8 | 6.6 | 4.8 | 3.6 | 4.9 | 4.3 | 6.8 | 5.0 | 8.3 | 7.7 | 5.9 | 7.1 | 6.7 | 7.0 | 7.4 |
ANGPTL4 | 4734 | 3225 | 13,651 | 8977 | 51,129 | 1.3 | 2.0 | 1.6 | 2.7 | 1.9 | 12.7 | 3.6 | 2.0 | 4.0 | 3.9 | 6.8 | 6.1 | 4.1 | 2.7 | 6.9 | 9.6 | 9.8 | 3.6 | 4.2 | 7.0 |
APOA4 | 552 | 536 | 47 | 196 | 456 | −1.3 | −2.6 | 2.2 | 1.3 | 1.1 | 1.2 | 8.6 | 1.7 | 1.4 | 1.3 | −1.6 | −1.1 | 1.4 | 2.0 | 1.2 | −1.1 | −1.1 | 1.4 | 1.0 | 1.7 |
APOC3 | 92,071 | 101,537 | 31,961 | 47,656 | 345 | −1.4 | −1.1 | −1.0 | 1.0 | −1.2 | 1.3 | −1.0 | 1.0 | −1.1 | −1.3 | 1.2 | 1.1 | 1.0 | −1.0 | −1.2 | 1.0 | −1.0 | 1.2 | −1.1 | −1.1 |
AQP3 | 1902 | 2013 | 1993 | 2981 | 360 | 2.4 | 2.3 | −1.1 | −1.2 | 1.2 | −1.4 | −1.5 | −1.8 | 1.1 | −1.4 | −1.2 | 1.6 | −1.2 | −1.6 | −1.1 | 1.3 | 1.0 | −1.9 | −1.5 | 1.0 |
AQP7 | 2802 | 2582 | 1227 | 1720 | 364 | −1.1 | 1.2 | 1.1 | 1.5 | 1.2 | 1.3 | 1.2 | 1.4 | 1.7 | 1.2 | 2.3 | 1.3 | 1.4 | 1.6 | 1.3 | 2.3 | 1.8 | 1.3 | 1.3 | 1.7 |
CPT1A | 123 | 76 | 114 | 128 | 1374 | 1.5 | 1.7 | 1.7 | 2.6 | 1.2 | 4.6 | 2.8 | 1.7 | 3.0 | 1.7 | 4.8 | 5.9 | 3.5 | 3.7 | 2.2 | 3.6 | 4.0 | 2.8 | 2.5 | 2.3 |
CPT1B | 150 | 116 | 172 | 163 | 1375 | 1.7 | 2.4 | −1.1 | −1.0 | −1.1 | 1.5 | −1.1 | −1.0 | −1.1 | −1.3 | 1.2 | 1.2 | −1.1 | −1.5 | −1.1 | 1.3 | 1.4 | −1.6 | −1.1 | −1.2 |
CPT2 | 2544 | 2443 | 1328 | 1882 | 1376 | 2.3 | 1.8 | 1.6 | 2.6 | 1.3 | 2.2 | 1.6 | 1.4 | 2.7 | 1.4 | 2.3 | 2.6 | 1.9 | 2.8 | 1.6 | 1.5 | 2.4 | 1.7 | 2.5 | 1.9 |
CROT | 159 | 118 | 88 | 56 | 54,677 | −2.4 | −2.2 | −1.7 | −1.9 | 1.0 | −1.4 | 1.0 | −1.6 | −1.6 | 1.1 | −1.2 | −1.2 | −1.3 | −2.0 | −1.1 | 1.1 | −1.2 | −1.6 | −1.6 | −1.0 |
CRP | 185 | 54 | 677 | 765 | 1401 | 1.1 | −1.8 | −1.0 | 1.2 | 1.6 | 1.5 | 1.4 | −1.0 | 1.1 | 2.4 | 2.6 | −1.5 | −1.1 | −1.0 | 2.2 | 1.6 | 1.5 | −1.8 | 1.0 | 1.9 |
CYP2B6 | 15,866 | 13,449 | 15,098 | 8823 | 1555 | 4.2 | 1.4 | 1.7 | 1.5 | 1.1 | 4.1 | 2.4 | 2.3 | 1.8 | 2.1 | −1.0 | −1.2 | −1.3 | −1.3 | 1.1 | 1.4 | 1.5 | 1.2 | 1.2 | 1.1 |
CYP3A4 | 65,886 | 64,170 | 3872 | 7344 | 1576 | 2.5 | −1.2 | 2.6 | 5.5 | 3.3 | 2.6 | 1.1 | 3.1 | 4.7 | 14.9 | −1.5 | −1.3 | −1.1 | 1.1 | 2.3 | −1.4 | −1.1 | 1.4 | 1.6 | 3.0 |
CYP4A11 | 329 | 299 | 68 | 82 | 1799 | 1.3 | 1.4 | 1.3 | 2.0 | −1.4 | 2.0 | 2.8 | 1.9 | 2.3 | −1.5 | 6.4 | 5.1 | 2.6 | 2.4 | 1.2 | 5.4 | 6.9 | 2.6 | 4.3 | 1.7 |
CYP4B1 | 2 | 2 | 2 | 2 | 30,666 | 1.1 | 1.1 | 3.1 | −1.1 | −1.2 | 1.1 | −1.0 | −1.0 | −1.0 | −2.5 | 1.1 | 1.1 | 1.0 | 1.1 | −1.6 | 1.2 | 1.1 | 1.2 | 1.0 | −1.7 |
CYP4F3 | 2491 | 2126 | 560 | 866 | 2313 | −1.0 | −1.3 | 1.4 | 1.1 | −1.2 | −1.3 | −1.6 | 1.2 | −1.6 | −1.4 | 1.2 | −2.9 | 1.2 | −3.5 | −1.1 | 1.1 | 1.4 | −1.8 | −1.6 | −1.5 |
CYP4F22 | 25 | 13 | 9 | 13 | 2028 | −2.4 | −1.7 | −1.1 | 1.1 | −1.1 | 1.0 | 1.7 | 1.5 | −1.1 | 1.3 | −1.5 | −1.5 | −1.1 | −1.2 | −1.3 | −1.5 | −1.6 | 1.3 | 1.3 | −1.2 |
CYP7A1 | 649 | 1472 | 85 | 10 | 3389 | −3.5 | −8.6 | −1.5 | −1.0 | −4.2 | −3.2 | 1.4 | −4.1 | 1.3 | −7.5 | −3.0 | −2.7 | −2.9 | 1.2 | −1.9 | −3.3 | −2.6 | −2.4 | −1.6 | −5.5 |
ELOVL6 | 388 | 720 | 542 | 586 | 79,071 | 1.8 | 1.8 | 1.3 | 1.6 | −1.0 | 1.4 | 1.5 | 1.4 | 1.6 | −1.0 | 1.2 | 1.1 | 1.9 | 1.8 | −1.1 | 1.8 | 1.2 | 1.4 | 1.4 | 1.1 |
FABP1 | 33,861 | 38,334 | 17,575 | 16,961 | 2168 | 3.6 | 5.3 | 1.9 | 3.4 | 1.4 | 1.7 | 4.0 | 1.8 | 3.3 | 1.5 | 5.2 | 2.7 | 3.4 | 4.4 | 2.6 | 4.6 | 2.5 | 3.0 | 4.2 | 2.7 |
FGF21 | 239 | 99 | 59 | 141 | 26,291 | 3.5 | 1.7 | 1.5 | 2.3 | −1.1 | 2.1 | 1.8 | 1.6 | 1.5 | 1.6 | 2.6 | 3.9 | 3.2 | 3.2 | 3.1 | 3.4 | 5.7 | 1.8 | 1.8 | 2.3 |
GK | 448 | 325 | 461 | 361 | 2710 | −1.0 | −1.2 | 1.3 | 1.2 | 1.5 | 1.2 | 1.4 | 1.3 | 1.4 | 1.4 | 1.8 | 2.0 | 1.9 | 2.2 | 1.6 | 1.7 | 1.7 | 2.0 | 2.0 | 2.0 |
HADHA | 2238 | 2530 | 1891 | 1845 | 8900 | 1.7 | 1.7 | 2.1 | 1.3 | 1.2 | 1.6 | 2.2 | 2.4 | 1.3 | 1.6 | 2.6 | 2.8 | 1.9 | 3.2 | 2.0 | 2.4 | 1.9 | 1.5 | 2.9 | 2.2 |
HMGCR | 4409 | 4550 | 2692 | 3599 | 3156 | −1.3 | −1.5 | −1.1 | −1.1 | −1.3 | −1.2 | −1.2 | −1.1 | −1.2 | −1.5 | −1.1 | −1.2 | 1.1 | 1.2 | −1.4 | −1.1 | −1.1 | 1.0 | 1.3 | −1.1 |
HMGCS1 | 10,529 | 11,863 | 6948 | 10,066 | 3157 | −1.4 | −1.9 | −1.2 | −1.3 | −1.5 | −1.4 | −1.0 | −1.6 | −1.7 | −1.6 | −1.1 | −1.4 | 1.3 | −1.0 | −1.5 | −1.2 | −1.5 | −1.3 | −1.1 | −1.1 |
IRF7 | 1440 | 1059 | 1108 | 1807 | 3665 | 2.3 | 2.4 | 1.1 | 2.0 | 2.3 | 2.6 | 2.1 | −1.1 | 1.7 | 2.5 | 3.5 | 2.5 | 1.2 | 1.2 | 3.5 | 3.6 | 3.4 | −1.1 | 1.2 | 3.0 |
LIPC | 13,012 | 6183 | 3955 | 3474 | 3990 | −1.5 | −1.5 | 1.3 | −1.2 | −1.2 | 1.4 | 1.1 | 1.3 | −1.0 | 1.1 | −1.3 | 1.2 | 1.8 | 1.4 | 1.2 | −1.2 | −1.3 | 2.1 | 1.3 | 1.3 |
MBL2 | 1461 | 1157 | 164 | 681 | 4153 | 3.1 | 1.6 | 1.9 | 2.5 | 2.5 | 6.9 | 3.8 | 3.6 | 3.4 | 2.7 | 3.9 | 3.7 | 2.9 | 3.0 | 2.9 | 3.9 | 4.0 | 2.7 | 4.4 | 2.9 |
PDK4 | 779 | 626 | 215 | 136 | 1987 | −1.9 | −2.3 | 3.2 | 1.8 | 1.7 | 2.7 | 3.9 | 4.3 | 3.1 | 7.2 | 5.8 | 11.8 | 10.0 | 10.9 | 11.6 | 5.5 | 9.7 | 10.0 | 11.1 | 20.4 |
PEX11A | 338 | 274 | 154 | 278 | 8800 | 1.3 | 1.2 | 1.4 | 1.8 | 1.8 | 3.2 | 2.5 | 1.8 | 2.4 | 2.5 | 5.3 | 3.9 | 2.9 | 2.7 | 3.1 | 4.1 | 4.0 | 2.5 | 2.4 | 3.7 |
PLIN4 | 448 | 344 | 986 | 552 | 114,782 | 4.2 | 4.2 | 1.2 | 1.6 | 3.3 | 1.8 | 2.5 | −1.0 | 1.8 | 2.9 | 4.7 | 4.4 | 1.1 | 1.1 | 4.5 | 4.7 | 5.6 | −1.0 | 1.4 | 4.1 |
PPARA | 472 | 626 | 540 | 444 | 1847 | −1.1 | −1.2 | −1.0 | −1.1 | 1.0 | −1.1 | −1.2 | −1.0 | −1.1 | −1.1 | −1.0 | 1.1 | −1.1 | 1.1 | −1.1 | −1.4 | −1.4 | −1.2 | 1.1 | −1.2 |
PPARG | 197 | 297 | 205 | 119 | 3640 | −1.3 | 1.1 | −1.0 | 1.1 | −1.1 | −1.3 | −1.3 | 1.1 | 1.0 | −1.3 | 1.0 | 1.1 | 1.1 | 1.0 | −1.1 | 1.3 | 1.2 | 1.1 | 1.0 | −1.1 |
SGK2 | 431 | 405 | 140 | 289 | 10,110 | 3.2 | 2.1 | 1.8 | 2.9 | 2.3 | 4.1 | 2.7 | 2.4 | 3.6 | 2.3 | 2.9 | 2.6 | 2.1 | 2.4 | 2.3 | 2.5 | 3.2 | 1.5 | 2.3 | 2.2 |
SLC2A2 | 3427 | 3496 | 1510 | 2724 | 6514 | −1.8 | −1.8 | −1.4 | −1.4 | −1.3 | −3.2 | −1.7 | −1.8 | −1.8 | −2.1 | −1.9 | −1.3 | −1.5 | −1.3 | −1.3 | −2.0 | −1.7 | −1.3 | −1.1 | −1.6 |
TXNIP | 637 | 846 | 456 | 1812 | 14,907 | 1.4 | −1.0 | 1.2 | 1.1 | 1.6 | 2.2 | 2.3 | −1.3 | 1.1 | 2.5 | 4.5 | 8.2 | 4.6 | 1.8 | 4.1 | 4.7 | 8.4 | 2.9 | 1.9 | 4.8 |
VLDLR | 339 | 205 | 244 | 539 | 7436 | 1.5 | 1.2 | 1.6 | 1.5 | 1.6 | 2.5 | 1.9 | 2.0 | 1.8 | 1.7 | 1.5 | 1.2 | 1.8 | 1.1 | −1.2 | 2.3 | 1.8 | 1.7 | 1.3 | 1.8 |
Miscellaneous genes | |||||||||||||||||||||||||
ABAT | 11,603 | 15,998 | 4899 | 5254 | 18 | −1.5 | −1.4 | −1.3 | −1.2 | −1.3 | −2.7 | −1.7 | −1.5 | −1.7 | −2.1 | −2.0 | −1.8 | −1.9 | −2.1 | −2.1 | −2.5 | −1.9 | −1.8 | −1.9 | −1.7 |
ABCB11 | 136 | 143 | 31 | 71 | 8647 | −1.3 | −2.5 | −1.3 | 1.1 | −1.6 | 1.1 | −1.6 | 1.1 | 1.3 | 1.1 | −2.0 | −1.9 | −1.1 | −1.0 | −1.4 | −3.3 | −3.3 | −1.7 | −1.4 | −1.3 |
ABCG5 | 7295 | 4665 | 2156 | 2672 | 387 | −1.5 | −1.5 | −1.0 | 1.0 | −1.3 | −1.1 | −1.1 | 1.0 | 1.0 | −1.5 | 1.0 | 1.2 | −1.2 | −1.2 | −1.1 | 1.1 | 1.0 | −1.3 | −1.0 | −1.1 |
BRCA1 | 698 | 371 | 105 | 92 | 662 | −2.4 | −2.3 | 1.1 | −1.1 | 1.4 | −1.6 | −6.0 | 1.0 | 1.0 | 2.0 | −3.2 | −1.7 | 1.0 | 1.1 | 1.3 | −3.8 | −1.9 | −1.1 | 1.1 | 1.2 |
CYP2E1 | 12,166 | 14,594 | 4600 | 1779 | 1571 | −2.2 | −2.9 | 1.0 | 1.2 | −1.0 | −2.7 | −2.2 | −1.0 | −1.4 | −1.9 | −1.2 | −1.7 | −1.0 | −1.2 | −1.1 | −2.3 | −1.9 | −1.2 | −1.1 | −1.1 |
CYP8B1 | 41,844 | 40,094 | 13,969 | 22,570 | 1582 | −1.0 | −1.3 | −1.1 | 1.0 | −1.5 | 1.0 | 1.0 | 1.3 | 1.1 | −1.4 | −1.0 | −1.0 | −1.1 | 1.0 | −1.0 | 1.2 | −1.1 | 1.2 | 1.6 | 1.1 |
DEFB1 | 72,067 | 28,637 | 36,921 | 5918 | 1672 | −1.3 | −1.1 | −1.1 | −1.2 | −1.6 | −2.5 | −1.1 | −1.2 | −1.6 | −1.2 | −1.6 | −1.2 | 1.2 | 1.1 | 1.2 | −1.5 | −2.3 | −1.0 | −1.4 | −1.1 |
EGR1 | 1296 | 1299 | 1691 | 2666 | 1958 | −1.3 | −1.5 | −1.2 | −1.3 | −1.0 | −2.5 | −1.3 | −1.4 | −1.4 | −1.3 | −1.4 | −1.3 | −1.0 | −1.1 | −1.2 | 1.2 | −1.2 | 1.2 | 1.3 | −1.4 |
GGT1 | 2014 | 1023 | 1672 | 584 | 2678 | 1.4 | 1.8 | −1.1 | −1.1 | −1.1 | 1.2 | −1.2 | −1.4 | −1.3 | −1.2 | −1.2 | −1.1 | −1.9 | −2.1 | 1.0 | −1.2 | −1.1 | −2.2 | −1.4 | 1.1 |
HAL | 116 | 348 | 363 | 425 | 3034 | −1.5 | −1.3 | −1.4 | −1.3 | −1.3 | −2.4 | 1.0 | −1.2 | −1.2 | −2.0 | 1.0 | −1.2 | −1.0 | 1.1 | −1.8 | 1.3 | −1.4 | −1.2 | 1.4 | −1.3 |
HHEX | 2090 | 1973 | 815 | 1224 | 3087 | −1.3 | −1.9 | 1.1 | 1.1 | 1.1 | −1.1 | −1.0 | 1.2 | 1.1 | 1.0 | −1.3 | −1.0 | 1.0 | 1.2 | −1.2 | −1.4 | −1.3 | −1.1 | 1.3 | −1.3 |
HIBCH | 7322 | 6926 | 5351 | 5998 | 26,275 | −1.3 | −1.3 | −1.1 | −1.2 | 1.0 | −1.4 | −1.1 | 1.0 | −1.1 | −1.1 | 1.1 | −1.0 | 1.1 | −1.0 | −1.1 | 1.1 | −1.1 | −1.1 | −1.0 | 1.0 |
HIF1A | 1119 | 845 | 3789 | 2599 | 3091 | −1.3 | −1.3 | 1.1 | −1.4 | −1.1 | −1.8 | 1.1 | 1.4 | −1.1 | −1.2 | −1.8 | −1.2 | 1.3 | 1.2 | −1.4 | −1.2 | −1.4 | 1.9 | 1.5 | −1.2 |
HMOX1 | 706 | 582 | 828 | 1860 | 17,090 | 6.4 | 9.7 | 1.5 | 1.3 | 1.6 | 1.1 | 1.3 | 3.1 | 2.0 | 2.2 | 2.6 | 1.2 | 3.3 | 2.5 | 3.9 | −1.2 | 1.3 | 5.3 | 2.4 | 2.5 |
HPX | 46,736 | 44,689 | 33,659 | 38,779 | 3263 | 1.1 | 1.2 | −1.2 | 1.2 | −1.4 | −1.3 | −1.3 | −1.1 | 1.1 | −1.5 | 1.1 | −1.2 | −1.5 | −1.2 | −1.4 | −1.2 | −1.2 | −1.7 | −1.1 | −1.2 |
ICAM1 | 972 | 787 | 3180 | 2782 | 3383 | 1.0 | −1.0 | −1.0 | −1.0 | 1.0 | −1.9 | −1.5 | −1.1 | −1.1 | 1.0 | −1.5 | −1.3 | −1.4 | −1.3 | −1.2 | −1.6 | −1.2 | −1.6 | −1.4 | −1.0 |
IGF1 | 993 | 1508 | 542 | 1120 | 858 | −3.3 | −1.9 | −1.6 | −1.3 | −1.1 | −2.4 | −3.9 | −1.5 | −1.2 | −1.1 | −1.4 | −2.6 | −1.0 | −1.1 | −1.1 | −2.1 | −3.0 | 1.1 | −1.5 | 1.1 |
IL1B | 32 | 12 | 59 | 51 | 3553 | −1.0 | −1.5 | 1.1 | 1.2 | 3.6 | −1.4 | 1.1 | 1.9 | 1.5 | 8.6 | −1.1 | 1.2 | 1.7 | 1.5 | 8.0 | −1.1 | 1.2 | 2.0 | −1.2 | 7.7 |
INSIG1 | 9795 | 15,138 | 3770 | 7152 | 3638 | −1.1 | −1.1 | 1.2 | 1.7 | −1.2 | −1.6 | −1.0 | 1.0 | 1.3 | 1.1 | 1.3 | −1.1 | 1.3 | 1.6 | −1.0 | −1.2 | −1.3 | −1.2 | 1.2 | −1.1 |
JUN | 6574 | 5213 | 4942 | 4495 | 3725 | −1.3 | −1.6 | −1.0 | 1.0 | 1.0 | −1.2 | −1.2 | −2.0 | −1.0 | 1.0 | −1.5 | −1.2 | −1.4 | −1.1 | 1.4 | −1.6 | −1.6 | −1.7 | −2.1 | 1.1 |
LBP | 10,370 | 3743 | 206,30 | 17,853 | 3929 | 1.4 | 1.4 | −1.0 | 1.2 | 1.1 | 1.2 | −1.4 | −1.2 | −1.1 | 1.0 | 1.2 | −1.1 | −1.4 | −1.1 | 1.0 | −1.3 | 1.4 | −1.7 | −1.2 | 1.2 |
LCAT | 556 | 511 | 199 | 238 | 3931 | −1.2 | −1.1 | −1.1 | −1.3 | −1.1 | −1.3 | −1.6 | −1.3 | −1.4 | −1.3 | −1.1 | −1.2 | −1.4 | −1.8 | −1.1 | −1.4 | −1.1 | −1.6 | −1.4 | −1.1 |
LDLR | 2452 | 2786 | 3724 | 3159 | 3949 | 1.2 | 1.1 | 1.2 | 1.0 | −1.1 | −1.2 | −1.2 | −1.1 | −1.1 | −1.1 | −1.1 | −1.2 | −1.1 | −1.1 | −1.2 | −1.3 | −1.0 | −1.3 | −1.2 | −1.0 |
LECT2 | 1262 | 1135 | 2796 | 1175 | 3950 | −1.7 | −1.2 | −1.3 | −1.7 | −4.1 | −1.2 | −1.3 | −1.3 | −1.6 | −5.5 | −1.0 | 1.0 | −1.5 | −1.6 | −7.3 | 1.3 | 1.4 | −1.2 | 1.2 | −2.6 |
MT1A | 99,558 | 68,833 | 109,515 | 59,968 | 4489 | 1.0 | 1.0 | −1.1 | 1.1 | −1.1 | 1.0 | −1.0 | 1.1 | 1.1 | −1.0 | −1.1 | −1.1 | 1.0 | 1.2 | −1.1 | −1.2 | −1.5 | −1.0 | −1.5 | −1.2 |
MYC | 750 | 655 | 1700 | 1712 | 4609 | 1.3 | −1.2 | −1.0 | 1.2 | −1.0 | −1.0 | 1.0 | 1.2 | 1.3 | 1.1 | −1.8 | 1.0 | 1.1 | 1.5 | −1.0 | −1.0 | 1.4 | 1.2 | 1.3 | −1.1 |
NR1I3 | 3594 | 4935 | 751 | 1014 | 9970 | −1.4 | −1.6 | −1.2 | 1.1 | −1.2 | −1.6 | −1.3 | 1.0 | −1.0 | −1.6 | −1.1 | −1.3 | −1.6 | −1.7 | −1.4 | −1.3 | −1.3 | −1.8 | −1.5 | −1.2 |
PECI | 26,767 | 30,088 | 14,949 | 22,812 | 10,455 | −1.2 | −1.3 | 1.1 | 1.0 | −1.0 | −1.1 | −1.1 | 1.1 | 1.1 | −1.1 | −1.2 | −1.1 | 1.1 | 1.0 | −1.1 | −1.3 | −1.2 | 1.1 | −1.1 | −1.0 |
PECR | 1631 | 1656 | 710 | 1446 | 55,825 | −1.1 | −2.0 | −1.3 | −1.4 | −1.3 | −1.3 | −1.4 | −1.6 | −1.4 | −1.5 | −1.1 | −1.1 | −1.1 | −1.2 | −1.4 | −1.3 | −1.1 | −1.4 | −1.1 | −1.1 |
SAA1 | 147,553 | 140,546 | 207,482 | 221,246 | 6288 | 1.6 | 1.5 | −1.1 | −1.2 | 1.0 | −3.4 | 1.2 | −1.2 | −1.3 | −1.2 | 1.1 | −1.1 | −1.2 | −1.4 | −1.0 | −1.0 | −1.1 | −1.5 | −1.3 | 1.2 |
TRO, troglitazone; ROSI, rosiglitazone; MURA, muraglitazar; TESA, tesaglitazar.