Pharmacokinetic parameters for hαhIL-10
Parameters were calculated using a noncompartmental model for intravenous administration.
| Parameter | hαhIL-10 12G8 (FELA) | hαhIL-10 12G8 (ELISA) |
|---|---|---|
| Dose (mg/kg) | 3.0 | 3.0 |
| Clearance (ml · day−1 · kg−1) | 8.48 | 8.25 |
| Vss (ml/kg) | 158.26 | 135.32 |
| AUClast (μg · day/ml) | 272.12 | 292.75 |
| t1/2 terminal (day) | 13.66 | 11.89 |