Percentages (mean ± S.D.) of excretory metabolites of CP-945,598 in healthy obese human subjects after oral administration of [14C]CP-945,598 (urine pooled from 0 to 384 h)
| Metabolite Number | m/z | Percentage of Dose | ||
|---|---|---|---|---|
| Urine | Feces | Total | ||
| Parent | 510 | 0.2 ± 0.1 | 1.4 ± 0.9 | 1.6 ± 0.9 |
| M1 | 482 | 2.3 ± 0.6 | 4.5 ± 0.5 | 6.8 ± 0.8 |
| M2 | 483 | 5.4 ± 1.5 | 30.9 ± 14.8 | 36.3 ± 15.5 |
| M3 | 498 | 0.6 ± 0.1 | 1.2 ± 0.6 | 1.8 ± 0.1 |
| M6 | 498 | 0.5 ± 0.1 | 1.9 ± 0.6 | 2.4 ± 0.7 |
| M9a | ND | ND | 6.3 ± 4.3 | 6.3 ± 4.3 |
| M17 | 674 | 4.8 ± 1.4 | ND | 4.8 ± 1.4 |
ND, not detected.