In vivo CLbile, int of drugs in rats
CLbile, int values were calculated according to eq. 7. Each value represents the mean ± S.D. (n = 5).
| Compound | CLbile, int |
|---|---|
| ml · h−1 · kg−1 | |
| Rosuvastatin | 150.3 ± 30.2 |
| Pravastatin | 403.4 ± 94.3 |
| Valsartan | 71.1 ± 15.6 |
| Olmesartan | 66.8 ± 6.0 |
| Cefmetazole | 214.0 ± 58.2 |
| Cefoperazone | 323.1 ± 58.5 |
| Cefpiramide | 201.4 ± 15.9 |
| Topotecan | 27.5 ± 2.5 |