TABLE 7

Product ions and structures of sunitinib and its proposed metabolites

MetaboliteStructure[M + H]+Fragment Ions
SunitinibEmbedded Image399.2196326, 283, 255, 238
M1Embedded Image371.1883326, 283, 255, 238
M2A,B,C,DEmbedded Image415.2067342, 299, 271, 254, 205
M2EEmbedded Image415.2067326, 283
M2FEmbedded Image415.2067326, 283, 255
M3Embedded Image343326, 283
M4A/C/DEmbedded Image387.1832342, 299
M4EEmbedded Image387.1832324, 283, 255
M5A/BEmbedded Image495.1713415, 342, 299
M6Embedded Image575.2517502, 459
M7A/B/CaEmbedded Image591.2466
M8Embedded Image397.2239324, 281, 253, 236
M9Embedded Image401328, 285, 177, 134
M10Embedded Image397.2040326, 283, 255, 238
M11Embedded Image358.1203283, 255, 238

  • ↵a No information on the fragment ions of M7A/B/C.