Isoform Specificity | Substrate | Human GSTM1-Null | Mouse Gstm1-Null | Substrate Classification |
---|---|---|---|---|
Total GSTs | CDNB | → | ↓a | Mouse specific |
Mu class GSTs | NBC | ↓ | ↓ | Common |
Mu class GSTs | DCNB | → (CLLOQ) | ↓a | Mouse specific |
Mu class GSTs | PBO | → (BLLOQ) | ↓ | Mouse specific |
→, no impact; ↓, decreased; CLLOQ, close to the lower limit of quantification; BLLOQ, below the lower limit of quantification.
↵a Data are cited on the basis of the findings in Fujimoto et al. (2006).