TABLE 2

Summary of the impact of GSTM1/Gstm1-null genotype on GST activities

Isoform SpecificitySubstrateHuman GSTM1-NullMouse Gstm1-NullSubstrate Classification
Total GSTsCDNBaMouse specific
Mu class GSTsNBCCommon
Mu class GSTsDCNB→ (CLLOQ)aMouse specific
Mu class GSTsPBO→ (BLLOQ)Mouse specific
  • →, no impact; ↓, decreased; CLLOQ, close to the lower limit of quantification; BLLOQ, below the lower limit of quantification.

  • a Data are cited on the basis of the findings in Fujimoto et al. (2006).