Summary of the impact of GSTT1/Gstt1-null genotype on GST activities
| Isoform Specificity | Substrate | Human GSTT1-Null | Mouse Gstt1-Null | Substrate Classification |
|---|---|---|---|---|
| Total GSTs | CDNB | → | →a | Not substrate |
| Theta class GSTs | DCM | ↓ | ↓a | Common |
| Theta class GSTs | EPNP | → (BLLOQ) | ↓a | Mouse specific |
→, no impact; ↓, decreased; BLLOQ, below the lower limit of quantification.
↵a Data are cited on the basis of the findings in Fujimoto et al. (2007).