TABLE 2

Electrospray ionization-generated molecular ions for compound P and metabolites in LC-MS before and after active H/D exchange

[M+H/D]+No. of Exchangeable H Atoms
Unlabeled14C-Labeled
m/z
P488→490490→4921
M1390→392392→3941
M2366→368368→3701
M3365→368367→3702
M4504→506506→5081
M5502→503504→5050
M6462→466464→4683