TABLE 1

Analysis conditions for UGT substrates

DrugInternal StandardMobile PhaseElectrospray IonizationTransition
QuercetinIndomethacin1Nega301→151
RaloxifeneDiazepam1Posi474→112
BazedoxifeneDiazepam1Posi471→126
DiclofenacIndomethacin1Nega294→250
Tolfenamic acidIndomethacin1Nega260→216
TolcaponeDiazepam1Posi274→182
EntacaponeDiazepam1Posi306→233
TelmisartanDiazepam1Posi515→276
GemfibrozilIndomethacin2Nega249→130
EtodolacIndomethacin2Nega286→242
IndomethacinDiclofenac2Nega356→312
  • Phase 1, 0.1% formic acid and 100% acetonitrile; phase 2, 5 mM ammonium formate with 5% acetonitrile and 100% acetonitrile; nega, negative; posi, positive.