Effect of chemical inhibitors on M1 formation from 5BPO (5 μM) in mouse liver cytosol (protein conc., 0.5 mg/ml)
| Inhibitor | Inhibitor Concentration | Target Enzyme | % M1 Formation at 30 Min |
|---|---|---|---|
| μM | |||
| No inhibitor (control) | 100 | ||
| Allopurinol | 100 | XO | 74 |
| Oxipurinol | 100 | XO | 90 |
| Methotrexate | 100 | XO | 97 |
| Raloxifene | 50 | AO | 7 |
| Menadione | 100 | AO | 0 |