Comparison between UGT1A9-TL and 1A9-XHC and HLM (pmol · min−1 · mg−1)
The different tails are listed in Table 1, and substrate concentrations are listed in Table 2. Data represent means ± S.D. (n = 3).
| Substrate | 1A9-TL | 1A9-XHC | HLM |
|---|---|---|---|
| 1-Naphthol | 89.5 ± 1.6 | 201.3 ± 2.6 | |
| 4-MU | 1593 ± 61 | 5155 ± 43 | |
| Entacapone | 4624 ± 310 | 14,251 ± 606 | 15,223 ± 1054 |
| Indomethacin, pH 7.4 | 48.9 ± 0.7 | 100.1 ± 0.6 | |
| Indomethacin, pH 6.0 | 62.1 ± 7.9 | 129.2 ± 6.4 | |
| Scopoletin | 1376 ± 216 | 4540 ± 193 |