trans-stimulation of rosuvastatin basolateral efflux in Caco-2 cells
Rosuvastatin (50 μM) and atenolol (10 μM) were codosed into the apical compartment at pH 5.5; rosuvastatin release in the basolateral compartment at pH 7.4 was measured in the absence (control) or the presence of taurolithocholate. Data are expressed as mean ± S.D. (n = 3).