Enzymes | Percentage of Conversion | ||
---|---|---|---|
NADPH | NADH | NAD+ | |
% | |||
Rat liver microsomes | 13.8 | 3.5 | N.D. |
Monkey liver microsomes | 15.8 | 2.0 | N.D. |
Human liver microsomes | 11.6 | 7.5 | N.D. |
Rat liver cytosol | 0.8 | N.D. | N.D.a |
Monkey liver cytosol | 2.5 | N.D. | N.D.a |
Human liver cytosol | 3.1 | N.D. | N.D.a |
N.D., not detected.
↵a The ketone metabolite (M31) was observed after incubation.