TABLE 4

Percentages of low spin and high spin in CYP1A1 and CYP1A2 in the absence and the presence of phenacetin or acetaminophen at 27°C

Enzyme (+Substrate)Low SpinHigh Spin
%
CYP1A1 (no substrate)955
    + Phenacetin937
    + Acetaminophen928
CYP1A2 (no substrate)8812
    + Phenacetin7129
    + Acetaminophen7921