No. | [M + H]+1 | Fragment Ions in MS/MS | Structure of Proposed Metabolites | Reactions | Source | Possible Substrate of the Metabolite |
---|---|---|---|---|---|---|
M1 | 255 | 239.11 | Demethylation | Urine/feces | DMF | |
M2 | 285 | 269.01 | Demethylation | Urine/feces | TMF | |
M3 | 315 | 298.67 285.17 270.75 256.33 | Demethylation | Urine/feces | 3,5,7,4′-Tetramethoxyflavone | |
M4 | 345 | 328.17 311.45 298.60 284.55 277.41 255.68 237.61 | Demethylation | Urine/feces | PMF | |
M5 | 349 | 268.78 254.26 | Demethylation, sulfation | Urine | DMF | |
M6 | 359 | 343.03 328.41 297.66 282.49 254.62 | Demethylation | Urine | PMF | |
M7 | 365 | 284.92 269.24 255.09 | Demethylation, sulfation | Urine | TMF | |
M8 | 379 | 298.38 284.37 269.17 254.87 | Demethylation, sulfation | Urine | TMF | |
M9 | 415 | 238.65 | Glucuronidation | Urine | DMF | |
M10 | 301 | 285.00 269.52 256.01 | Demethylation | Feces | 3,5,7,4′-Tetramethoxyflavone | |
M11 | 331 | 315.49 299.97 285.69 268.42 255.94 | Demethylation | Feces | PMF |