Clearances (CLtot) of fentanyl and propofol during therapeutic hypothermia
Significance evaluated with Mann-Whitney U test. Values presented as median [semi-interquartile range]. Lower and upper bounds of confidence intervals (CIs) presented as (lower, upper).
| Drug | CLtot of Drug in: | 95% CI for Difference | |
| Hypothermic (n = 14) Group | Normothermic (n = 8) Group | ||
| ml/min | |||
| Fentanyl | 726 [230]* | 1331 [678] | (−1440, −27) |
| Propofol | 2046 [305]* | 2665 [223] | (−1343, −106) |
↵* P < 0.05.