Percentages (mean ± S.D.) of circulating metabolites of ertugliflozin in humans after administration of a single 25-mg oral dose of [14C]-ertugliflozin (N = 6)
| Metabolite | Percentage of Radioactivity |
|---|---|
| Ertugliflozin | 49.9 ± 5.0 |
| M1 | 2.5 ± 1.0 |
| M2 | 1.3 ± 0.3 |
| M4a | 12.2 ± 1.1 |
| M4b | 4.1 ± 0.8 |
| M4c | 24.1 ± 7.5 |
| M5a | 6.0 ± 2.2 |