Medication history
Summary of the administered preoperative medications known to influence (induce or inhibit) cytochrome P450 (CYP) activity.
| Drugs | No. of Patients Receiving the Drug | Affected CYP Isoform(s) | Reference |
|---|---|---|---|
| Inhibiting drugs | |||
| Retinol | 14 | CYP2C9, 2C19 | (Hamman et al., 1997; Yamazaki and Shimada, 1999) |
| Cholecalciferol | 13 | CYP2C9, 2C19, 2D6 | (Yamazaki and Shimada, 1999) |
| Somatostatin | 4 | CYP2D6, 3A4 | (Rasmussen et al., 1998) |
| Sulfamethoxazole | 1 | CYP2C9 | (Venkatakrishnan et al., 2000) |
| Fluconazole | 2 | CYP2C9, 2C19 | (Venkatakrishnan et al., 2000) |
| (Es)omeprazole | 8 | CYP2C9, 2C19 | (Li et al., 2004) |
| Amlodipine | 1 | CYP2C9, 2D6, 3A4 | (Ma et al., 2000) |
| Ciprofloxacine | 1 | CYP1A2, 3A4 | (Fuhr et al., 1992; McLellan et al., 1996) |
| Propranolol | 5 | CYP1A2, 2D6 | (Kudo et al., 1997; Tassaneeyakul et al., 1993) |
| Inducing drugs | |||
| (Es)omeprazole | 8 | CYP1A2 | (Rost et al., 1992) |
| Rifampicin | 7 | CYP2C9, 2C19, 3A4 | (Sousa et al., 2008) |