TABLE 1

Mean percentage of radioactivity recovered following i.v. administration of compound A or B at 15 mg/kg to Sprague Dawley rats (n = 3 per sex)

Matrix% Radioactivity Recovered in 0–240 Hours
ABB (male)a
Urine62.326.227.2
Feces25.129.432.2
Expired airN.D.N.D.27.5
Totalb92.258.795.1
  • N.D., not determined.

  • a Samples were collected at 0–168 hours.

  • b Includes carcass and cage rinse.