Effect of genotype variants across sex/ethnicity cohorts (N=100)
Values are expressed as mean estimates of log10 (MR) ± (95% confidence intervals).
| Genotype | CAM (n = 25) | CAW (n = 25) | AAW (n = 25) | HAW (n = 25) |
|---|---|---|---|---|
| Wild type (only) | 0.774 (0.648–0.901) | 0.812 (0.672–0.952) | 0.845 (0.678–1.013) | 0.726 (0.460–0.992) |
| Intron 3 (only) | 0.638 (0.530–0.746) | 0.676 (0.567–0.784) | 0.500 (0.314–0.686) | 0.680 (0.540–0.819) |
| Exon 5 (only) | 0.587 (0.480–0.693) | 0.624 (0.518–0.731) | 0.614 (0.496–0.731) | 0.643 (0.494–0.792) |
| Exon 9 (only) | 0.809 (0.659–0.960) | 0.847 (0.689–1.004) | 0.900 (0.579–1.221) | 0.600 (0.324–0.847) |
AAW, African-American women; CAM, Caucasian-American men; CAW, Caucasian-American women; HAW, Hispanic-American women; MR, metabolic ratio.