TABLE 1

Demographics, BEI, and Clbiliary of [3H]taurocholate in sandwich-cultured human hepatocytes

Donors had no history of tobacco or alcohol use or comedications; body mass index (BMI); sandwich-cultured hepatocytes were incubated with 1 μM [3H]taurocholate (10 minutes). Results are presented as representative data from triplicate determinations in two livers.

Liver Donor
IdentificationAgeGenderRaceBMITaurocholate
BEI %In Vitro Clbiliary
yrkg/m2ml/min/kg
Liver 144FemaleCaucasian2464.859.9
Liver 248FemaleCaucasian21.762.632.4