Time course for the percentage of total detected 14C radioactivity of ADP and metabolites derived from 14C-ADP in urine after intravenous injection of 3H- and 14C-radiolabeled H12-(ADP)-liposomes at a dose of 10 mg lipids/kg to rats
Each value represents the mean ± S.D. (n = 4).
| Time Course | Allantoin | ADP | Uric Acid | Hypoxanthine | Xanthine |
|---|---|---|---|---|---|
| 6 h | 89.7 ± 12.2 | 1.3 ± 1.2 | N.D. | N.D. | N.D. |
| 1 day | 78.7 ± 13.3 | 16.0 ± 15.8 | N.D. | N.D. | N.D. |
| 3 day | 71.8 ± 15.9 | N.D. | N.D. | N.D. | 11.2 ± 10.5 |
| 5 day | 75.0 ± 20.8 | N.D. | 3.9 ± 3.4 | N.D. | 6.7 ± 5.9 |
N.D., not determined.