TABLE 2

Correlations of rifampin-induced changes in the mRNA expression among the clinically important P450 genes

Values represent the correlation coefficients (R values).

	CYP2A6	CYP2B6	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP3A4	CYP3A5	CYP4F2
CYP1A2	0.08	0.54	0.75	0.49	0.16	−0.12	0.48	−0.36	0.46
CYP2A6		0.75	0.29	0.62	0.79	0.76	0.90	−0.36	0.50
CYP2B6			0.72	0.67	0.58	0.29	0.79	−0.11	0.48
CYP2C19				0.31	−0.05	−0.16	0.51	−0.38	0.44
CYP2C8					0.76	0.64	0.75	−0.15	0.86
CYP2C9						0.77	0.77	−0.13	0.43
CYP2D6							0.68	−0.30	0.62
CYP3A4								−0.57	0.67
CYP3A5									−0.39