The measured and estimated concentration of BIIB021 and its metabolites in the AUC pooled (0–4 hours) plasma samples of patients after oral administration of BIIB021
| Patient | A | B | C | D | E | F | |
|---|---|---|---|---|---|---|---|
| ng/ml | |||||||
| Measured | BIIB021 | 284 | 592 | 215 | 179 | 478 | 619 |
| M3 | 322 | 76.9 | 328 | 478 | 74.5 | 549 | |
| M7 | 493 | 92.1 | 344 | 451 | 285 | 652 | |
| M4 | 212 | 50 | 206 | 691 | 87 | 156 | |
| Estimated | M10 | 218 | 293 | 237 | 225 | 322 | 346 |