Relative distribution of benzo[a]pyrene (BaP) metabolites in the liver, spleen, and head kidney microsomes of control and untreated trout
The sum of metabolites that were extracted from microsomal incubations correlates to 100%. Values in parentheses are the amount of picomoles of substance per milligram of protein per hour.
| Liver | Spleen | Head Kidney | ||||
|---|---|---|---|---|---|---|
| Control | BaP-Treated | Control | BaP-Treated | Control | BaP-Treated | |
| 3-OH | 52.7% (0.39) | 22.2% (2.1) | n.d. | n.d. | 59.6% (0.05) | 32.1% (0.2) |
| 7,8-diol | 31.7% (0.24) | 45.7% (4.4) | 73.1% (0.04) | 64.1% (0.073) | 40.4% (0.035) | 40.8% (0.26) |
| 9,10-diol | 1.9% (0.02) | 8.7% (0.8) | n.d. | 7.5% (0.009) | n.d. | 7.4% (0.046) |
| 9-OH | 13.7% (0.1) | 23.4% (2.2) | 26.9% (0.016) | 28.4% (0.03) | n.d. | 19.7% (0.12) |
| Total metabolites | 100% (0.75) | 100% (9.5) | 100% (0.056) | 100% (0.112) | 100% (0.085) | 100% (0.63) |
n.d., not detected.