LC-MS data of drug-containing rat bile (I) and the bile sample hydrolyzed by β-glucuronidase (II)
| Retention Time | XICa | [M-H]− in XIC | Identification | |
|---|---|---|---|---|
| І | ІІ | |||
| min | Intensity (% Base Peak) | m/z | ||
| 16.56–16.61 | 4.76 × 105 (100) | 1.03 × 106 (100) | 493 | SAA |
| 34.54–34.58 | 7.23 × 105 (100) | 7.39 × 105 (100) | 507 | Monomethyl SAA |
| 29.69–29.76 | 4.34 × 105 (60) | 1.99 × 105 (27) | ||
| 30.74–30.76 | 3.61 × 104 (5) | 1.85 × 105 (25) | ||
| 41.57–41.55 | 4.66 × 105 (100) | 1.74 × 106 (100) | 521 | Dimethyl SAA |
| 44.33–44.31 | 3.73 × 105 (80) | 5.22 × 105 (30) | ||
| 44.87–44.91 | 3.35 × 105 (72) | 1.09 × 106 (63) | ||
| 38.51–38.60 | 1.72 × 105 (37) | 3.31 × 105 (19) | ||
| 47.89–47.95 | 1.11 × 105 (24) | 6.96 × 104 (4) | ||
| 62.80–62.84 | 2.98 × 105 (100) | 3.65 × 105 (100) | 535 | Trimethyl SAA |
| 52.19–52.22 | 4.47 × 104 (15) | 4.02 × 104 (11) | ||
| 10.50–10.52 | 1.37 × 106 (100) | 669 | SAA glucuronide | |
| 18.25–18.28 | 1.14 × 106 (100) | 683 | Monomethyl SAA glucuronide | |
| 13.61–13.66 | 7.07 × 105 (62) | |||
| 12.24–12.26 | 4.67 × 105 (41) | |||
| 17.26–17.28 | 2.51 × 105 (22) | |||
| 20.54–20.56 | 1.71 × 105 (15) | |||
| 25.16–25.18 | 2.84 × 106 (100) | 697 | Dimethyl SAA glucuronide | |
| 31.23–31.26 | 1.51 × 106 (53) | |||
| 16.40–16.42 | 4.97 × 105 (27) | |||
| 10.86–10.88 | 3.86 × 105 (21) | |||
| 19.34–19.36 | 3.68 × 105 (20) | |||
| 34.64–34.66 | 3.95 × 105 (100) | 711 | Trimethyl SAA glucuronide | |
| 29.36–29.39 | 2.37 × 105 (60) | |||
| 21.92–21.94 | 1.58 × 105 (40) | |||
↵a Only those peaks with intensity larger than 3.5 × 104 are listed.