Mass balance: excretion and recovery of total radiolabeled components of male CD-1 mice following a single intravenous administration of [3H]-SBB siRNA in LNP vehicle (nominal dose: 2.5 mg/kg)
Values are the percentage of dose.
| [3H]-SSB in LNP Vehicle | Urine | Feces | Carcass | Tritiated Water | Total |
|---|---|---|---|---|---|
| 48 h | 14 | 2 | 46 | 18 | 80 |
| 168 h | 18 | 3 | 16 | 53 | 90 |
| 504 h | 18 | 3 | 9 | 80 | 110 |