TABLE 4

Determination of nicotine, nornicotine, cotinine, norcotinine, and trans-3′-hydroxycotinine in plasma from HIV-1–positive and HIV-negative smokers

Patient	CD4 Count	Nicotine	Cotinine	Trans-3′-Hydroxycotinine	Nornicotine	Norcotinine
		ng/ml
HIV-negative smokers
1	1416	10.87	2.33	2.28	4.10	0.88
2	938	33.07	115.55	68.19	3.97	2.45
3	1488	14.85	123.38	24.33	2.15	1.61
4	1289	27.49	84.93	4.86	1.65	1.19
5	742	28.96	79.51	94.19	3.61	3.28
6	936	53.06	65.49	3.43	2.91	0.63
7	1438	61.59	119.04	71.65	1.91	3.87
8	1039	51.45	98.37	33.28	1.64	2.42
9	500	17.10	23.59	1.50	2.46	0.87
10	700	31.86	38.45	18.86	2.94	1.17
11	921	36.91	98.02	20.12	1.09	1.15
12	1032	40.11	106.47	19.42	1.26	1.02
13	1382	49.78	117.30	65.88	1.52	2.11
14	594	18.90	33.68	8.02	1.70	0.84
15	838	39.76	69.86	8.09	4.05	1.47
16	977	10.85	4.57	3.31	0.58	0.54
17	1009	39.36	93.30	56.26	0.76	2.40
Mean ± S.D.		33.29 ± 15.414	74.93 ± 40.526	29.63 ± 29.853	2.24 ± 1.187	1.62 ± 0.987
HIV-1–positive smokers
1	110	10.50	197.00	115.60	5.30	5.50
2	584	6.50	56.00	34.10	4.70	1.60
3	13	1.90	75.80	12.20	4.50	1.30
4	540	12.30	85.40	14.00	5.70	1.40
5	412	7.20	95.10	22.50	8.40	2.20
6	235	4.60	16.10	1.90	12.00	0.60
Mean ± S.D.		7.17 ± 3.801	87.57 ± 64.464	33.38 ± 41.699	6.77 ± 2.924	2.10 ± 1.746