KD and Bmax of CS-1036 in rat and monkey plasma, and rat and human amylase
| Species | Source | KD | CV | Bmax | CV |
|---|---|---|---|---|---|
| (nM) | (%) | (nM) | (%) | ||
| Rat | Plasma | 8.95 | 26.2 | 52.8 | 8.6 |
| Salivary amylase | 5.64 | 19.9 | 95.4 | 3.3 | |
| Monkey | Plasma | 27.2 | 38.6 | 22.1 | 20.9 |
| Human | Salivary amylase | 4.92 | 50.3 | 52.1 | 11.8 |
| Pancreatic amylase | 8.74 | 44.3 | 81.6 | 11.0 |