Meana relative UGT2B expression levels in human tissue specimens
| Tissue Site | UGT2B4 | UGT2B7 | UGT2B10 | UGT2B11 | UGT2B15 | UGT2B17 | |
|---|---|---|---|---|---|---|---|
| Liver | Mean | 1.0E+00 | 5.6E-01 | 1.4E-01 | 9.6E-03 | 1.6E-02 | 5.0E-02 |
| S.E. | 5.9E-01 | 3.9E-01 | 1.1E-01 | 7.6E-03 | 8.8E-03 | 4.4E-02 | |
| % Total | 56.6% | 31.5% | 7.6% | 0.5% | 0.9% | 2.8% | |
| # BLQ | 0 of 27 | 0 of 27 | 0 of 27 | 0 of 27 | 0 of 27 | 4 of 27 | |
| Lung | Mean | 4.2E-03 | 1.6E-03 | 1.7E-03 | 2.4E-02 | 2.3E-03 | 1.5E-02 |
| S.E. | 1.6E-03 | 1.8E-03 | 1.5E-03 | 2.7E-02 | 2.0E-03 | 1.0E-02 | |
| % Total | 8.8% | 3.4% | 3.5% | 49.2% | 4.9% | 30.3% | |
| # BLQ | 0 of 22 | 11 of 22 | 8 of 22 | 1 of 22 | 9 of 22 | 3 of 22 | |
| Larynx | Mean | 7.0E-03 | BLQ | 6.9E-03 | 9.3E-03 | 1.2E-03 | 1.5E-02 |
| S.E. | 6.1E-03 | — | 6.2E-03 | 9.1E-03 | 1.0E-03 | 7.8E-03 | |
| % Total | 17.6% | — | 17.4% | 23.7% | 3.2% | 38.1% | |
| # BLQ | 0 of 7 | 7 of 7 | 0 of 7 | 0 of 7 | 0 of 7 | 0 of 7 | |
| Esophagus | Mean | 8.3E-04 | 9.4E-04 | 9.3E-04 | 1.7E-03 | 2.9E-03 | 2.4E-03 |
| S.E. | 5.7E-04 | 1.8E-03 | 7.1E-04 | 1.2E-03 | 2.8E-03 | 2.2E-03 | |
| % Total | 8.6% | 9.6% | 9.5% | 17.7% | 30.3% | 24.3% | |
| # BLQ | 1 of 13 | 10 of 13 | 3 of 13 | 1 of 13 | 3 of 13 | 0 of 13 | |
| Tonsil | Mean | 5.5E-02 | BLQ | 4.3E-02 | 6.0E-02 | 1.5E-02 | 1.0E-01 |
| S.E. | 9.0E-02 | — | 7.6E-02 | 7.7E-02 | 2.2E-02 | 5.5E-02 | |
| % Total | 20.2% | — | 15.8% | 22.0% | 5.3% | 36.8% | |
| # BLQ | 0 of 22 | 22 of 22 | 1 of 22 | 0 of 22 | 5 of 22 | 0 of 22 | |
| Floor of mouth | Mean | 3.5E-03 | BLQ | 3.4E-03 | 5.2E-03 | 5.9E-04 | 7.1E-03 |
| S.E. | 6.0E-03 | — | 5.6E-03 | 8.6E-03 | 9.5E-04 | 4.7E-03 | |
| % Total | 17.6% | — | 17.3% | 26.1% | 3.0% | 36.0% | |
| # BLQ | 0 of 3 | 3 of 3 | 0 of 3 | 0 of 3 | 0 of 3 | 0 of 3 | |
| Tongue | Mean | 3.1E-03 | BLQ | 2.5E-03 | 2.1E-03 | BLQ | 1.6E-03 |
| S.E. | 6.5E-03 | — | 4.6E-03 | 3.4E-03 | — | 1.5E-03 | |
| % Total | 33.3% | — | 26.9% | 22.8% | — | 17.0% | |
| # BLQ | 0 of 3 | 3 of 3 | 1 of 3 | 0 of 3 | 3 of 3 | 0 of 3 | |
| Pancreas | Mean | 1.7E-03 | 3.4E-02 | 1.2E-03 | 1.7E-03 | 3.1E-02 | 1.8E-02 |
| S.E. | 9.2E-04 | 2.9E-02 | 2.5E-04 | 8.9E-04 | 4.3E-02 | 3.6E-02 | |
| % Total | 2.0% | 38.5% | 1.4% | 1.9% | 35.5% | 20.7% | |
| # BLQ | 8 of 16 | 1 of 16 | 10 of 16 | 5 of 16 | 0 of 16 | 3 of 16 |
BLQ, below the limit of quantification.
↵a Arithmetic mean of all samples in a given tissue, normalized to the mean hepatic expression of UGT2B4.